Resources:
Cell by cell characterization
Go beyond population averages to capture and resolve cellular heterogeneity.
Rapid single cell profiling
Partition hundreds to tens of thousands of nuclei or cells per chip in minutes.
Compact and flexible
Small instrument footprint easily integrates into existing laboratory infrastructure.
One system, many single cell approaches
Resolve complex biology
Uncover molecular insights and resolve highly complex biological systems. Capture the full heterogeneity of a sample, in tens of thousands of cells.
Explore Biology Like Never Before: Chromium Single Cell Solutions
Multiomic cellular readout
Gain more insights from precious samples. Measure mRNA, cell surface proteins, immune clonotype, antigen specificity, CRISPR perturbations, and chromatin accessibility. Uncover molecular insights, dissect cell-type differences, investigate the innate and adaptive immune system, detect novel subtypes and biomarkers, and map the epigenetic landscape, cell by cell.
Single cell RNA sequencing can help connect datasets for multiple dimensions to reveal a rich picture of cell phenotypes
Flexible workflow
Our suite of Chromium Single Cell products has been validated on fixed, fresh, and frozen samples, as well as whole cells and nuclei. Leverage biological insights with easy-to-use analysis and visualization software.
Getting Started with Single Cell Gene Expression
Proven Results
Proven Results
Resources
Find the latest app notes and other documentation for Chromium Controller.
Getting Started with Single Cell Gene Expression
Getting Started with Single Cell Gene Expression
Experiment Planning Guide, 10x Genomics
Experiment Planning Guide, 10x Genomics
Tools for Discovering Biology at True Resolution
Tools for Discovering Biology at True Resolution
Product Offerings from 10x Genomics
Product Offerings from 10x Genomics
The Power of Single Cell Partitioning
The Power of Single Cell Partitioning
Chromium Technology Brochure, 10x Genomics
Chromium Technology Brochure, 10x Genomics
Publications
Search peer-reviewed publications using Chromium Controller
Single-Cell Transcriptome and Antigen-Immunoglobin Analysis Reveals the Diversity of B Cells in Non-Small Cell Lung Cancer.
Single-Cell Transcriptome and Antigen-Immunoglobin Analysis Reveals the Diversity of B Cells in Non-Small Cell Lung Cancer.
Genome Biology. 2020, J Chen, et al.
Genome Biology. 2020, J Chen, et al.
COVID-19 Severity Correlates with Airway Epithelium-Immune Cell Interactions Identified by Single-Cell Analysis.
COVID-19 Severity Correlates with Airway Epithelium-Immune Cell Interactions Identified by Single-Cell Analysis.
Nature Biotechnology. 2020, RL Chua, et al.
Nature Biotechnology. 2020, RL Chua, et al.
Human and Mouse Single-Nucleus Transcriptomics Reveal TREM2-Dependent and TREM2-Independent Cellular Responses in Alzheimer’s Disease.
Human and Mouse Single-Nucleus Transcriptomics Reveal TREM2-Dependent and TREM2-Independent Cellular Responses in Alzheimer’s Disease.
Nature Medicine. 2020, Y Zhou, et al.
Nature Medicine. 2020, Y Zhou, et al.
Our End-to-End Solution
Chromium Controller
Our compact instrument
Our automated instrument
Chromium Single Cell Reagents
With our reagent kits, capture and amplify mRNA, profile the immune repertoire, identify CRISPR perturbations, detect chromatin accessibility, and more.
Analysis and Visualization Software
Convert your data to biologically meaningful insights and interactively explore your results with easy-to-use software.
World-Class Technical and Customer Support
Our expert support team can be contacted by phone or email.
Frequently Asked Questions
The Chromium Controller has a small instrument footprint that easily integrates into existing laboratory infrastructure.
Weight: 12.5 lb (5.6 kg)
Size: (W X D X H) 7.9 x 10.3 x 6.4 in (20 x 26.3 x 16.4 cm)
Ventilation Requirement: Minimum 4 in (10 cm) around all sides
Electrical Requirements: Nominal 100–240 Vac, 50–60 Hz, 25 W, from a standard 3-prong wall receptacle that includes a safety ground pin
Usable Temperature Range: 18–28°C (64–82°F)
Humidity: 85% Max (Non-Condensing)
Altitude: 0–6,560 ft (0–2,000 m)
For additional information, see the Chromium Controller Specifications manual
The Chromium Controller is compatible with our suite of Chromium Single Cell products, including Single Cell Gene Expression, Single Cell Immune Profiling, and Single Cell ATAC. Capture molecular readouts of cell activity in multiple dimensions, including gene expression, cell surface proteins, immune clonotype, antigen specificity, and chromatin accessibility.
Chromium Single Cell products require a number of assay-dependent reagents and consumables. Explore our Product Selector to determine the components necessary for your application. Additional kits, reagents, and laboratory equipment are required. Please see individual kit User Guides, available on our Support website for further details.
You can process between 1–8 samples in one run, loading up to 10,000 cells per sample.
Decontamination should be performed in accordance with institutional guidelines. For general guidance on how to clean the Chromium Controller, please review our Chromium Controller Specifications documentation
Compatible Products
Single Cell Gene Expression
Profile cell types and states with 3' gene expression, surface protein expression, and CRISPR perturbations in the same cell.
Single Cell Immune Profiling
Analyze full length paired BCRs/TCRs, surface protein expression, antigen specificity, and 5' gene expression in the same cell.
Single Cell Multiome ATAC + Gene Expression
Explore combined gene expression and chromatin accessibility data from the same cell to uncover gene regulatory programs.
Single Cell ATAC
Reveal the epigenomic landscape and analyze chromatin accessibility cell by cell to decipher gene regulatory mechanisms.
Targeted Gene Expression
Profile a defined set of transcripts from single cells or fresh frozen tissue sections to focus on the genes that matter most.